Wednesday, October 8, 2008

Question - 76


Identify all visuals and connect.

Answer: The people are Osamu Shimomura (top left), Martin Chalfie (bottom left) and Roger Tsien, the 2008 chemistry Nobel laureates. They studied a green fluorescent protein (GFP) produced by the Jellyfish Aequorea Victoria and modified it to serve as a cell marker. The green mice are a result of such experiments as are the spectacular "brainbows" shown in the bottom right. The gene that creates the GFP was first isolated by Douglas Prasher of the Woods Hole Oceonographic institute which he freely provided to both Tsien and Chalfie. Sadly, Prasher lost his job due to lack of grants and now drives a courtesy shuttle for a car dealership in Huntsville, Alabama. Arvind, Divya, Mekhala, Hirak, RajeshK, Ashwin, Iam, Adi and Rahul Trivedi got it. Well done.

14 comments:

Unknown said...

I think this is the experiment where they have used jellyfish DNA to make certain Rat organs fluorescent to UV or something. To be used like a tracer for cancer/disease or rate of growth studies..... whatever, it makes the rats ears and tails look fluorescent green....
Am guessing the humanoids in the visuals are the researchers who are workin on it, since THEIR Ears arent green

Anonymous said...

Sappa matter ba.
This year's Nobel Chemistry winners.
The fluorescent jellyfish that inspired them to create their Green Fluoro protein.

Divya said...

transgenic mice (jellysifh -> mice), brainbow

Raghu said...

2008 Nobel Prize for Medicine

mekie said...

The 2008 Chemistry Nobel laureates (Chalfie, Shimomura and Tsien)for isolating and developing the green fluorescent protein (GFP) from jellyfish. Other color mutants of the fluor. protein - cyan, blue, yellow - have been developed too.

hirak said...

Nobel - jellyfish protein GFP

Anonymous said...

The 2008 Nobel for Chemistry(Martin Chalfie of Columbia University, Osamu Shimomura of the Marine Biological Laboratory in Woods Hole, Mass., and Roger Y. Tsien of UC San Diego). Extracted protein responsible for the green color of jelly fish under UV radiation.

Interesting bit of info: The researchers could not get the gene separation of the jelly fish. They borrowed it from the discoverer at NIH (dont know his name though). That guy is out of job in research field and is driving a shuttle service for a Birmingham, AL car dealership.

Rajesh K

Unknown said...

Osamu Shimomura, Martin Chalfie and Roger Tsien. They share the Nobel prize for chemistry in 2008, for the discovery of green fluorescent protein (GFP) from jellyfish. The other two pictures are GFP mice exhibiting fluorescence in their ears and cells/membranes expressing fluorescence

Anonymous said...

Connect GFP protein and 2008 Nobel prize - Chemistry

Bio-fluoresence (Brainbow)
3 dudes are Osamu Shimomura, Roger Tsien & Martin Chalfie the recipients

Pics - GFP mice, Jelly fish that actually made GFP but was robbed of its Nobel prize, Brainbow neurons and Axons

Anonymous said...

Connect : GFP and Nobel Prize = Chemistry

3 dudes : Osamu Shimomura, Roger Tsien & Martin Chalfie

Pics: GFP mice, Jellyfish that first made GFP but was robbed of the Prize, Brainbow neurons and axons

Anonymous said...

This year's noble prize in chemistry for green fluroscent protien

Rahul Trivedi said...
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Rahul Trivedi said...
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Rahul Trivedi said...

GFP - in the original post I pluralized "mouse" to "mouses" and thus mortified, deleted the post:) So, here's only the short answer.